The University of Cambridge (UCAM) was founded in 1208 and is the fourth oldest University in the world. In 2017 it was ranked as the top research university in the UK and currently recognised as the second best university in the world according to the Times Higher Education listings. The Department of Biochemistry is a member of the School of the Biological Sciences and one of the largest departments in the University of Cambridge. The Department is especially strong in research with investigators of international standing in a wide range of disciplines including structural biology, molecular enzymology, cell signalling and control of gene expression, molecular microbiology, plant molecular biology and bioenergy, cancer and cardiovascular biology. The department has world class facilities in mass spectrometry for metabolomics, lipidomics and proteomics. In addition through the Cambridge Systems Biology Centre we have access to expertise in computer programming, bioinformatics and mathematical modelling. Main tasks in the project – UCAM will perform all the lipidomics detailed in the proposal (WP2-5).
Prof. Dr. Julian Griffin focuses on the development of metabolomics and lipidomics tools to investigate aspects of the Metabolic Syndrome (http://www.bioc.cam.ac.uk/uto/griffin.html). In addition he has a long standing interest in the use of lipidomics and metabolomics as a tool for toxicology. His group has been at the centre of the development of metabolomics/metabonomics as a research tool in biochemistry, particularly its application to medical diagnostics, personalised medicine and toxicology.
Dr Cecilia Castro has wide experience of a range of metabolomics approaches and bioinformatics tools and will manage the day-to-day running of the project.